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Valsartan
Release date:2013-06-20 Browsing times:次
CAS NO. 137862-53-4
English name Valsartan
Chemical name N-(1- valeryl)-N-[4-[2-(1H- tetrazole -5- pyridyl) phenyl] phenmethyl]-L- Valine
Chemical Classification pharmaceutical intermediates
Chemical formula C24H29N5O3
Specification USP30
Storage Condition cool,dry, room-temperature and well-closed container
Guaranteed Analysis
Appearance white or almost white crystalline powder
Identify IR must conform to reference standard
HPLC must conform to reference standard
Absorbance ≤0.02
Moisture ≤2.0%
Residue on ignition ≤0.1%
Heavy Metals ≤0.001%
Relate Compounds
Compound A ≤0.1%
Compound B ≤0.2%
Compound C ≤0.1%
Any other individual impurity ≤0.10%
Total impurity (excluding R-isomer) ≤0.3%
Residual solvents
Ethyl acetate ≤0.5%
Dichloromethane ≤0.06%
Methanol ≤0.3%
N,N-Dimethylformamide: ≤0.088%
Assay (HPLC) 98.0~102.0%
physical characteristics
White or almost white crystalline powder, odorless, slightly moist. easily dissolved in methanol and ethanol ,
sparingly soluble in ethyl acetate, slightly soluble in dichloromethane, almost insoluble in water.
usage
Valsartan is used clinical for receptor antagonist of angiotensin AT1, has good effect to the different degree of
hypertension patients who used other antihypertensive drugs without efficacy , is a new generation of highly
efficient antihypertensive drugs.
package
In 25kg per fiber drum inner polythene bags。
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